Asthma and Diesel Soot
Asthma cause: Secret Agent
"There's a man who lives a life of danger,
To everyone he meets, he stays a stranger,
With every move he makes,
Another chance he takes,
Odds are he won't live to see tomorrow."
Secret Agent Man, The Ventures, 1966
Could diesel exhaust be a cause of asthma, rather than just a trigger? Acute exposures, such as
running an engine in a closed space, are known causes of asthma attacks. But what
about chronic lower level exposure, like riding in a car? Could asthma causing immune system changes develop over a long period of time as a result of air quality in cars?
Note: this article is not intended as scientific analysis or medical advice. Its purpose is to alert readers
to an unsuspected asthma and allergy causing hazard. We take driving for granted, doing it from cradle to grave, often feeling
more threatened by our TV imagery than the real risk we are taking. Those of us with a predisposition
to allergies and asthma need to look carefully for asthma causation.
I remember coming over the pass into the Los Angeles basin for the first time. The year was 1967.
It seemed like there was a forest fire, the sky was black. Emissions controls imposed over the years
have made the visibility and color better, but that improvement is in some ways a deception.
Coarse particulate
matter in the air has declined during those years, but levels of invisible fine particulate matter
(less than 2.5 micron size), are still health threatening. One source of fine particles is
vehicle exhaust.
It is impossible for asthmatics to avoid exposure to these inflammation causing fumes.
Diesel engines move over three million commercial vehicles in America.
Many of these motors are decades old, accumulating as many as a quarter million
miles annually. Maintenance is often delayed until a failure occurs. Top end
overhauls, which include rebuilt injector nozzles, are easiest to forgo. But
scarred and unclean injectors waste fuel, which pours out unburned,
a gray-white color instead of the usual black.
Asthma Cocktail: Shaken, not Stirred
The toxic, sooty cocktail from truck stacks is a well-known health hazard.
It contains hundreds of chemicals, including
toxins, carcinogens, and reproductive hazards.
Multiple studies have associated diesel emissions with tumor genisis.
Particulate matter, commonly referred to as soot,
is made up of small carbon particles covered with many types of toxic molecules.
Fine particles act as carriers of these carcinogenic compounds
into the body. Ultrafine particles, less than .1 micron in diameter, make up over 80%
of soot (by numbers, not weight). These are lung penetrators, able to slip
through the network of hairs and
natural filters in the airways.
Experts disagree on whether the carbon core or the molecules stuck to it
are the real causes, but regardless of the actual mechanism, these particles are dangerous to everyone, especially those with asthma.
Ultrafines cause inflammation and scarring of the small sacks in the lungs (alveoli). Such
a particle with Mercury or Cadmium on its surface will provoke immune cells to
abandon the search for viral or bacterial invaders, attacking the toxin carrier instead.
Particulates and Asthma
Fine particulate, known to be an asthma trigger, may also cause immune system
changes which worsen or induce asthma.
Studies find a relationship between asthma attacks and
proximity to major roadways. The closer to a major highway, the more serious the asthma.
It appears that diesel exhaust can cause allergic sensitization. Sulphur dioxide and Nitrogen
dioxide gasses can directly instigate the inflammatory response. However it is particulate matter
which invades tissues that really reorganizes the immune response, predisposing the person to asthma.
Evidence suggests
that chronic exposure to truck exhaust particles at low concentrations causes increased
expression of cytokines, chemokines, and
production of IgE antibodies. These mediators of inflammation are the
essence of allergy and asthma. Adding oxidant
stress in airway tissues, and you have a precursor state to asthma.
Fine particulate can even cause an increased response to normal allergens, increasing IgG mediated long
term asthmatic and allergic reactions. These changes take place over time, so it's never too late
to evaluate the environment in your car cabin.
Fumes build up in tunnels or on construction sites where unregulated
off-road diesels work. Truck engines are not designed for prolonged idling, and
much unburned vapor permeates the areas near truck stops.
EPA recently adopted strong air borne emissions standards for
newly manufactured diesel engines. This reduced demand for new trucks, with many
overhauls of existing fleets. It will be at least 2030 before emissions are reduced.
Since moving to Houston, I try to drive only when traffic is light, like first thing
Sunday
morning. After 40 years in various roady situations, I absolutely refuse to sit in traffic.
The automobile is a poor candidate for a refuge from asthma, being a particle trap
built entirely of toxic materials.
I consider a real air purifier for the car essential for anyone with asthma or allergies. For me, it is a stopgap measure against the recurrence
of my debilitating allergies and MCS. If you or a loved one are asthmatic, don't overlook the good
old American road in your search for possible causes of asthma.
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